May is Brain Cancer Awareness Month
Please join the AACR in supporting brain cancer research.
Each year more than 23,000 people in the United States are diagnosed with
brain cancer and other nervous system cancers, according to federal statistics. These cancers make up a portion of the nearly 78,000 brain tumors diagnosed each year in this country.
There are many types of brain and spinal cord tumors. The tumors are formed by the abnormal growth of cells and may be either benign or malignant. Benign brain and spinal cord tumors grow and press on nearby areas of the brain. They rarely spread into other tissues and may recur.
Malignant brain and spinal cord tumors are likely to grow quickly and spread into other brain tissue.
When a tumor grows into or presses on an area of the brain, it may stop that part of the brain from working the way it should. Both benign and malignant brain tumors produce signs and symptoms and need treatment.
Tumors that start in the brain are called primary brain tumors. Primary brain tumors may spread to other parts of the brain or to the spine, but rarely spread to other parts of the body. Often, tumors found in the brain have started somewhere else in the body and spread to one or more parts of the brain. These are called metastatic brain tumors.
Metastatic brain tumors are more common than primary brain tumors. About half of metastatic brain tumors are from lung cancer.
May is Brain Cancer Awareness Month.
The National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) Program estimates that more than 16,830 people in the U.S. will die from brain and other nervous system cancers in 2018.
What the AACR Is Currently Doing in This Area
The American Brain Tumor Association has graciously donated funds for the AACR-American Brain Tumor Association Scholar-in-Training Awards to support young investigators who present high-quality abstracts in brain cancer research for both primary and secondary (metastatic) brain tumors at the AACR Annual Meeting 2018. These awards went to: Damian A. Almiron Bonnin of the Geisel School of Medicine at Dartmouth, for his study, "HEY1-mediated inhibition of glioma stem cell proliferation is associated with restoration of glioma stem cell division asymmetry and transcriptional repression of PDGFRA;" Samirkumar B. Amin, MBBS, PhD of The Jackson Laboratory for Genomic Medicine, for his study, "Genomic profiling of canine glioma: Comparative analyses with respect to drivers of human glioma;" Peiwen Chen, PhD, of The University of Texas MD Anderson Cancer Center, for his study, "Lysyl oxidase secreted by PTEN-deficient glioblastoma cells recruits macrophages and promotes malignant growth;" Islam Hassan, MD, of The University of Texas MD Anderson Cancer Center, for his study, "A radiomic-based MRI phenotype is uniquely associated with hypermutated genotype in gliomas;" and Mohammad Belayat Hossain, PhD, of The University of Texas MD Anderson Cancer Center, for his study, "Histone tyrosine phosphorylation determines glioblastoma cell survival."
Jayanta K. Das, PhD, of Florida International University, was awarded a 2018 AACR Minority and Minority-Serving Institution Faculty Scholars in Cancer Research award for his brain cancer-focused study, "Exosomal ID3 is pro-metastatic through guiding NRF1-induced breast cancer stem cells across the blood-brain barrier."
In 2018, two of the AACR-June L. Biedler Scholar-in-Training Awards went to researchers focusing on brain cancer: Chao Zhang, of the University of South Florida for his study, "Ligand-independent EphA2 signaling drives an amoeboid phenotype that promotes melanoma brain metastasis development;" and Li Xia, PhD, of Stanford University for his study, "Linked read whole-genome sequencing reveals pervasive chromosomal level instability and novel rearrangements in brain metastases from colorectal cancer."
The AACR's mission is to
prevent and cure all forms of cancer.
Source: National Cancer Institute
Last year the AACR provided over $64 million in grants and awards funding lifesaving cancer research. There are many ways you can support our mission to prevent and cure all cancers.